Daymuse Studios is utilizing the Omega Drupal Theme for the foundation of this site's design now. The theme offers a skeleton framework to base responsive design on within the Drupal CMS.
Omega is a responsive, mobile-first base theme leading the way in Drupal theming that supports HTML5, CSS3 and mobile, fluid, 720, 960 and 1200px (and custom) grids out of the box, giving you full control over your layout, advanced region placement and controls, and contextual layouts provided by the Delta and Context modules.
The cross-browser, mobile-first, responsive design allows us to build out adaptable interfaces that work great on smartphones and on desktops. This is an exciting step for the company's web presence and will also lead to further integration of the same concepts within our client/customer relationships.